Contraindications to hyperthermia treatment are:

• age over 70 years;
• pregnancy;
• organ pathology with organ dysfunction;
• drug allergy, anaphylactic reactions, Quincke’s edema;
• progressive drug addiction;
• traumatic brain injury, massive stroke, violation of cerebral circulation in the anamnesis;
• massive tumors of the spinal column with compression of the spinal cord;
• myocardial infarction;
• arrhythmias;
• hemorrhagic anemia;
• tuberculosis in open form, active phase;
• renal-hepatic insufficiency;
• metastases to the spine with severe neurological deficit;
• pathological fractures of tubular bones;
• insulin-dependent diabetes;
• mental illness;
• decompensation of the cardiovascular system;
• severe respiratory failure;
• severe homeostasis disorders;
• small functional reserves and adaptive capacity;   
• massive malignant tumors (more than 60 grams) and tumors located on large vessels, trachea and bronchi, large nerve trunks, the lysis of which can cause a threat to the patient’s life (bleeding, etc.).